Oxytocin Acetate | CAS 6233-83-6 | Neurohypophyseal Peptide Hormone (Research Use Only) | Knowlux

Product Description

Oxytocin Acetate, CAS 6233-83-6, is a synthetic cyclic nonapeptide hormone supplied by Knowlux for laboratory research use. It is the acetate salt of oxytocin (free base CAS 50-56-6), a posterior pituitary hormone involved in uterine smooth muscle contraction and mammary gland function. The molecular formula is C43H66N12O12S2.C2H4O2 (equivalently C45H70N12O14S2) and the molecular weight is 1067.24 g/mol. Each lot is released with a lot-specific COA, MSDS and full analytical traceability.

Salt form and CAS clarification: CAS 6233-83-6 is consistently recorded across ChemicalBook, MedChemExpress and Carl ROTH as oxytocin acetate (monoacetate salt). The free base form corresponds to CAS 50-56-6. The peptide sequence is Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 with a disulfide bridge between Cys1 and Cys6. Knowlux supplies the acetate salt explicitly and declares the counter-ion on each COA. Oxytocin is approved as a prescription medicine (Pitocin, Syntocinon) for labor induction and postpartum hemorrhage in many jurisdictions; that approval is specific to the finished pharmaceutical product and does not extend to this research-grade supply.

Product Parameters

Product Details

1. Overview

Oxytocin is a cyclic nonapeptide hormone synthesized in the hypothalamus and released from the posterior pituitary. Its primary physiological roles are stimulation of uterine smooth muscle contraction during parturition and ejection of milk from the mammary gland during lactation. The peptide was the first polypeptide hormone to be sequenced and synthesized, work that earned Vincent du Vigneaud the Nobel Prize in Chemistry in 1955. In research settings, oxytocin is studied as a model neuropeptide for receptor pharmacology (OXTR), social behaviour, and reproductive physiology. Knowlux supplies oxytocin acetate as a research-grade peptide for laboratory and analytical use; this supply is not intended for human administration and does not constitute a finished drug product.

2. Mechanism of Action (Research Context)

Published research describes oxytocin as an agonist of the oxytocin receptor (OXTR), a class A G protein-coupled receptor. Receptor activation is primarily Gq-coupled, leading to phospholipase C activation, IP3-mediated calcium release, and smooth muscle contraction. In the uterus, this signalling cascade increases contractile frequency and amplitude; in the mammary gland, it triggers myoepithelial cell contraction and milk ejection. Oxytocin also acts centrally, where it has been investigated for effects on social cognition, trust, and anxiety-related behaviours in research models. These descriptions are derived from published research and are provided for scientific reference only. Knowlux makes no claims regarding the efficacy, safety, or suitability of this product for any human application. Promotion of oxytocin for labor induction, lactation support, or any clinical or behavioural indication is not supported by Knowlux and is inconsistent with research-use-only supply.

3. Quality Control

Full COA, MSDS, and lot-specific chromatograms are issued with each shipment. Custom specifications and third-party inspection can be arranged.

4. Applications

• Reference standard for oxytocin receptor agonist analytical method development

• OXTR binding and functional assay development

• Uterine smooth muscle and mammary gland physiology research models

• Neuropeptide behaviour and social cognition research models

• LC-MS and immunoassay calibrators

5. Packaging, Storage & Shipping

Lyophilized powder: amber glass vial under nitrogen headspace, sealed with butyl stopper and aluminium crimp. Secondary packing: tamper-evident, light-protected carton with desiccant. Cold-chain shipping with validated gel packs and temperature logger; dry ice for -20 C shipments. COA, MSDS, packing list and certificate of origin issued with each shipment.

6. Documentation Support

Per lot: COA, MSDS, certificate of origin, residual solvent statement, counter-ion specification. Regulatory packages (specification summaries, audit support) available on a project basis.

About Knowlux

Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.

Compliance Statement

This product is supplied for laboratory research use only. It is not for human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Oxytocin is approved as a prescription medicine (Pitocin, Syntocinon) in many jurisdictions for labor induction and postpartum hemorrhage; that regulatory status is specific to the approved pharmaceutical product and does not extend to this research-grade supply as sold by Knowlux. Oxytocin acetate carries a GHS classification of H302 (harmful if swallowed), H360 (may damage fertility or the unborn child) and H413 (aquatic toxicity). Research context statements are for scientific reference only and do not constitute medical advice, promotional claims, or dosing guidance.