Aniracetam | CAS 72432-10-1 | AMPA Receptor Modulator (Research Use Only) | Knowlux

Product Description

Aniracetam, CAS 72432-10-1, is a synthetic racetam-family compound supplied by Knowlux for laboratory research use. It is also known as 1-(4-methoxybenzoyl)-2-pyrrolidinone or aniracetam. The molecular formula is C12H13NO3 and the molecular weight is 219.24 g/mol. Each lot is released with a lot-specific COA, MSDS and full analytical traceability.

Regulatory status clarification: Aniracetam is not approved by the FDA for any indication in the United States. It has been approved in a limited number of countries (Colombia, Egypt, Greece, Italy) but with no approved indications listed in the source database. The FDA has issued a recall for a dietary supplement found to contain undeclared aniracetam, reinforcing that it is not a permitted supplement ingredient in the US. Commercial listings frequently describe aniracetam as a nootropic or cognitive enhancer; those designations attach to unregulated supplement markets and do not apply to, and are not represented by, this research-grade lot.

Product Parameters

Product Details

1. Overview

Aniracetam is a member of the racetam family, structurally related to piracetam but distinguished by a 4-methoxybenzoyl group attached to the pyrrolidinone nitrogen. Unlike piracetam, aniracetam is lipid-soluble, a property that influences its distribution in research models. It was developed in the 1970s and has been studied primarily for its effects on cognitive parameters in preclinical and clinical research settings. Knowlux supplies aniracetam as a research-grade material for laboratory and analytical use; this supply is not intended for human administration and does not constitute a finished drug or supplement product.

2. Mechanism of Action (Research Context)

Published research describes aniracetam as a positive allosteric modulator of the AMPA receptor, a glutamate-gated ion channel involved in fast excitatory synaptic transmission. By slowing the rate of ion-channel closing, aniracetam is reported to enhance glutamatergic neurotransmission and long-term potentiation in research models. It has also been investigated for effects on other neurotransmitter systems, though the AMPA receptor interaction is the most consistently reported mechanism. These descriptions are derived from published research and are provided for scientific reference only. Knowlux makes no claims regarding the efficacy, safety, or suitability of this product for any human application. Promotion of aniracetam for memory enhancement, cognitive improvement, anxiety reduction, or any health benefit is not supported by Knowlux and is inconsistent with research-use-only supply.

3. Quality Control

The specification failures that matter most in aniracetam supply are related to residual starting materials from the synthesis (4-methoxybenzoic acid derivatives) and moisture uptake. Buyers should require a specific chromatographic assay and a declared limit for related substances, not a generic purity figure. Full COA, MSDS, and lot-specific chromatograms are issued with each shipment.

4. Applications

• Reference standard for aniracetam analytical method development

• In vitro AMPA receptor binding and functional assay development

• Glutamatergic neurotransmission and long-term potentiation research models

• Comparative studies of racetam-family compounds

• LC-MS and biochemical assay calibrators

5. Packaging, Storage & Shipping

Powder: amber glass vial or high-barrier foil bag under nitrogen headspace, sealed with tamper-evident closure. Secondary packing: light-protected carton with desiccant. Ambient or cold-chain shipping with temperature logger where required. COA, MSDS, packing list and certificate of origin issued with each shipment.

6. Documentation Support

Per lot: COA, MSDS, certificate of origin, residual solvent statement, heavy metal statement. Specification summaries and audit support available on a project basis.

About Knowlux

Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.

Compliance Statement

This product is supplied for laboratory research use only. It is not for human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Aniracetam is not FDA-approved for any indication in the United States, and the FDA has identified undeclared aniracetam in a recalled dietary supplement, reinforcing its non-permitted status as a supplement ingredient. Aniracetam carries a GHS classification of H361 (suspected of damaging fertility or the unborn child); appropriate handling precautions should be observed. Research context statements are for scientific reference only and do not constitute medical advice, promotional claims, or dosing guidance.