Uridine | CAS 58-96-8 | Pyrimidine Nucleoside (Research Use Only) | Knowlux

Product Description

Uridine, CAS 58-96-8, is a synthetic pyrimidine nucleoside supplied by Knowlux for laboratory research use. It consists of uracil linked to a ribose ring through a beta-N1-glycosidic bond, and is a fundamental metabolite required for RNA synthesis and membrane phospholipid formation. The molecular formula is C9H12N2O6 and the molecular weight is 244.20 g/mol. Each lot is released with a lot-specific COA, MSDS and full analytical traceability.

Identity and formula clarification: CAS 58-96-8 is consistently recorded across PubChem, Sigma-Aldrich and ChemicalBook as uridine, with formula C9H12N2O6 and molecular weight approximately 244.20. One ChemicalBook supplier listing reports 224.201, which is inconsistent with the accepted value and is not adopted here. Uridine is the predominant circulating pyrimidine in humans, with plasma levels maintained at 3-5 micromolar. Knowlux supplies the synthetic material and declares the counter-ion and assay basis on each COA.

Product Parameters

Product Details

1. Overview

Uridine is a pyrimidine nucleoside composed of uracil and ribose. It is synthesised de novo in the liver and kidney and circulated to peripheral tissues, where it serves as a key precursor in the pyrimidine salvage pathway. Beyond its role in RNA synthesis, uridine monophosphate (derived from uridine) is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Knowlux supplies uridine as a research-grade material for laboratory and analytical use; this supply is not intended for human consumption and does not constitute a finished food or supplement product.

2. Research Context (Not a Therapeutic Claim)

Published literature describes uridine as a metabolite studied in in vitro and in vivo research models, with proposed roles in phospholipid synthesis, mitochondrial function and neurotransmitter regulation. It has been investigated in research models of nervous system function and metabolic parameters. These descriptions are derived from published research and are provided for scientific reference only. Knowlux makes no claims regarding the efficacy, safety, or suitability of this product for any human application. Promotion of uridine for neurological benefits, anti-aging, or any health benefit is not supported by Knowlux and is inconsistent with research-use-only supply.

3. Quality Control

The specification failures that matter most in uridine supply are related to residual uracil from hydrolysis and moisture uptake. Buyers should require a specific chromatographic assay and a declared limit for residual uracil, not a generic purity figure. Full COA, MSDS, and lot-specific chromatograms are issued with each shipment.

4. Applications

• Reference standard for uridine analytical method development

• In vitro pyrimidine salvage pathway and RNA synthesis research

• Phospholipid metabolism and membrane biosynthesis studies

• Mitochondrial function and energy metabolism research models

• LC-MS and biochemical assay calibrators

5. Packaging, Storage & Shipping

Powder: amber glass vial or high-barrier foil bag under nitrogen headspace, sealed with tamper-evident closure. Secondary packing: light-protected carton with desiccant. Ambient or cold-chain shipping with temperature logger where required. COA, MSDS, packing list and certificate of origin issued with each shipment.

6. Documentation Support

Per lot: COA, MSDS, certificate of origin, residual solvent statement, heavy metal statement, residual uracil report. Specification summaries and audit support available on a project basis.

About Knowlux

Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.

Compliance Statement

This product is supplied for laboratory research use only. It is not for human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Uridine is sold as a dietary supplement ingredient in some jurisdictions and is used as a pharmaceutical intermediate; those regulatory positions attach to compliant supply chains and do not apply to, and are not represented by, this research-grade lot. Research context statements are for scientific reference only and do not constitute medical advice, promotional claims, or dosing guidance.