|
- Brand：Knowlux
- Model：Bottle/Aluminum foil bag/Drum/Customized to your needs
- Purity：99%
- Cas：78628-80-5
- Createtime： 2026-11-06
- Updatetime： 2026-11-03
| useage | medical intermediate，Pharmaceutical Intermediates |
| deliveryInfo | |
| appearance | White to off-white crystalline powder |
| aliasen | |
| supplyCapacity | 10MT/Month |
| harbor | Hong Kong, Shanghai, Shenzhen |
| minorder | 1KG |
| Molecular Formula: | C21H26ClN |
| Sample Available | Yes |
Terbinafine Hydrochloride | CAS 78628-80-5 | Allylamine Antifungal (Research Use Only) | Knowlux
Product Description
Terbinafine Hydrochloride, CAS 78628-80-5, is a synthetic allylamine derivative supplied by Knowlux for laboratory and pharmaceutical research use. It is also known as Lamisil. The molecular formula is C21H26ClN and the molecular weight is 327.89 g/mol. Each lot is released with a lot-specific COA, MSDS and full analytical traceability.
Product Parameters
| Item | Specification |
|---|---|
| Product Name | Terbinafine Hydrochloride |
| Synonyms | Lamisil; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine hydrochloride |
| CAS No. | 78628-80-5 |
| Molecular Formula | C21H26ClN |
| Molecular Weight | 327.89 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 204-208 C |
| Solubility | Soluble in methanol (50 mg/mL); slightly soluble in water |
| Purity | >=98.0% (HPLC); >=99.0% available on request |
| Identity | Confirmed by HPLC and UV-Vis |
| Grade | Pharmaceutical research grade |
| Storage | 2-8 C, protected from light and moisture |
| Hazard Statements | H315 (skin irritation); H319 (serious eye irritation); H335 (respiratory irritation); H400/H410 (aquatic toxicity) |
| HS Code | 2921.49.00 |
| Packaging | 5 g / 10 g / 50 g / 100 g / 1 kg foil bag or vial; bulk on request |
| MOQ | 10 g (research grade); 100 g (bulk) |
| Supply Ability | Gram to kilogram scale |
| Application | Laboratory and pharmaceutical research use only |
| Origin | China |
1. Profile
Terbinafine Hydrochloride is a synthetic allylamine antifungal, first approved by the FDA in 1992. It is widely studied and used clinically against dermatophyte infections of skin, hair and nails. Knowlux provides research-grade terbinafine hydrochloride for lab and pharmaceutical research only. It is not for direct human or veterinary administration and is not a finished drug.
2. Research Context (Not a Therapeutic Claim)
Published literature describes terbinafine as an allylamine derivative studied in in vitro and in vivo research models, with a mechanism involving inhibition of squalene epoxidase and blockade of ergosterol biosynthesis in fungal cell membranes. These descriptions are derived from published research and are provided for scientific reference only. Knowlux makes no claims regarding the efficacy, safety, or suitability of this product for any human or veterinary application. Promotion of terbinafine hydrochloride for antifungal treatment or any clinical indication is not supported by Knowlux and is inconsistent with research-use-only supply.
3. Quality Control
| Test Item | Method |
|---|---|
| Purity | HPLC |
| Identity | HPLC retention time / UV-Vis spectrum |
| Appearance | Visual |
| Moisture | Karl Fischer |
| Related substances | HPLC |
| Residual solvents | GC (on request) |
| Heavy metals | ICP-MS (on request) |
Full COA, MSDS, and lot-specific chromatograms are issued with each shipment.
4. Applications
-
Reference standard for analytical method development
-
In vitro antifungal susceptibility and mechanism studies
-
Pharmaceutical formulation and stability studies
-
LC-MS and biochemical assay calibrators
5. Packaging, Storage & Shipping
Powder: amber glass vial or high-barrier foil bag under nitrogen headspace, sealed with tamper-evident closure. Secondary packing: light-protected carton with desiccant. Ambient or cold-chain shipping with temperature logger where required. COA, MSDS, packing list and certificate of origin issued with each shipment.
6. Documentation Support
Per lot: COA, MSDS, certificate of origin, residual solvent statement, heavy metal statement. Specification summaries and audit support available on a project basis.
About Knowlux
Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.
Compliance Statement
This product is supplied for laboratory and pharmaceutical research use only. It is not for direct human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Amoxicillin is a prescription drug substance in many jurisdictions; that regulatory status is separate from this research-grade supply and does not extend to the product as sold by Knowlux. Amoxicillin is subject to GHS hazard classification (H302, H317, H334); appropriate handling precautions should be observed. Research context statements are for scientific reference only and do not constitute medical advice, promotional claims, or dosing guidance.
