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- Brand：Knowlux
- Model：Bottle/Aluminum foil bag/Drum/Customized to your needs
- Purity：99%
- Cas：2920938-90-3
- Createtime： 2026-11-06
- Updatetime： 2026-11-03
| useage | medical intermediate，Pharmaceutical Intermediates |
| deliveryInfo | |
| appearance | White Powder |
| aliasen | |
| supplyCapacity | 10MT/Month |
| harbor | Hong Kong, Shanghai, Shenzhen |
| minorder | 1G |
| Molecular Formula: | C39H54N10O10S |
| Sample Available | Yes |
N-Acetyl Semax Amidate | CAS 2920938-90-3 | Neuropeptide (Research Use Only) | Knowlux
Product Description
N-Acetyl Semax Amidate, CAS 2920938-90-3, is a synthetic heptapeptide supplied by Knowlux for research use. It is an N-terminally acetylated and C-terminally amidated analogue of Semax, with the sequence Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2. The molecular formula is C39H54N10O10S and the molecular weight is 854.97 g/mol. Each lot is released with a lot-specific COA, MSDS and full analytical traceability.
Product Parameters
| Item | Specification |
|---|---|
| Product Name | N-Acetyl Semax Amidate |
| Synonyms | Acetyl Semax; N-Acetyl Semax; AC-SEMAX; Ac-Semax Acetate |
| CAS No. | 2920938-90-3 |
| Molecular Formula | C39H54N10O10S |
| Molecular Weight | 854.97 g/mol |
| Sequence | Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2 (Ac-MEHFPGP-NH2) |
| Sequence Length | 7 amino acids |
| Key Structural Features | N-terminal acetylation; C-terminal amidation |
| Appearance | White to off-white lyophilized powder |
| Purity | >=98.0% (HPLC); >=99.0% available on request |
| Identity | Confirmed by LC-MS and peptide mapping |
| Grade | Research grade |
| Counter-ion | Acetate or TFA (lot-specific, declared on COA) |
| Moisture | <=8.0% (Karl Fischer) |
| Storage | -20 C, protected from light and moisture; reconstituted solution 2-8 C, use within 7 days |
| HS Code | 2937.90.00 |
| Packaging | 5 mg / 10 mg / 50 mg / 100 mg / 1 g vial; bulk and OEM on request |
| MOQ | 10 mg (research grade); 1 g (bulk) |
| Supply Ability | Gram to kilogram scale |
| Application | Research use only |
| Origin | China |
Product Details
1. Overview
N-Acetyl Semax Amidate is a synthetic analogue of Semax, a heptapeptide derived from the ACTH(4-10) fragment. The parent peptide sequence is Met-Glu-His-Phe-Pro-Gly-Pro. In this analogue, the N-terminus is acetylated and the C-terminus is amidated, modifications that enhance resistance to exopeptidase degradation and improve stability relative to the unmodified peptide. The product is supplied as a research-grade peptide and is not approved for any therapeutic use.
2. Mechanism of Action (Research Context)
Published preclinical literature describes Semax and its analogues as modulating BDNF/NGF expression, melanocortin receptor signalling, and neurotransmitter balance in the central nervous system. These mechanism descriptions are derived from published research on Semax-related peptides and are provided for scientific reference only. Knowlux does not make any claims regarding the efficacy or safety of this product for any application.
3. Quality Control
| Test Item | Method |
|---|---|
| Purity | RP-HPLC |
| Identity & molecular mass | LC-MS (deconvoluted) |
| Primary structure | Peptide mapping / amino acid analysis |
| Counter-ion content | Ion chromatography (acetate or TFA) |
| Moisture | Karl Fischer |
| Appearance | Visual |
| Related substances | RP-HPLC |
| Microbial limits | Membrane filtration (on request) |
Full COA, MSDS, and lot-specific chromatograms are issued with each shipment.
4. Applications
-
Reference standard for analytical method development
-
In vitro peptide stability and degradation studies
-
Research on neuropeptide structure-activity relationships
-
LC-MS and immunoassay calibrators
5. Packaging, Storage & Shipping
Lyophilized powder: amber glass vial under nitrogen headspace, sealed with butyl stopper and aluminium crimp. Secondary packing: tamper-evident, light-protected carton with desiccant. Ambient or cold-chain shipping with temperature logger where required. COA, MSDS, packing list and certificate of origin issued with each shipment.
6. Documentation Support
Per lot: COA, MSDS, certificate of origin, residual solvent statement. Specification summaries and audit support available on a project basis.
About Knowlux
Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.
Compliance Statement
This product is supplied for laboratory research use only. It is not for human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Mechanism statements are for scientific reference only and do not constitute medical advice or promotional claims.
