Spermidine | CAS 124-20-9 | Polyamine (Research Use Only) | Knowlux

Product Description

Spermidine, CAS 124-20-9, is a synthetic polyamine supplied by Knowlux for laboratory research use. It is a triamine with the chemical name N-(3-aminopropyl)-1,4-butanediamine. The molecular formula is C7H19N3 and the molecular weight is 145.25 g/mol. The product is air-sensitive and hygroscopic; each lot is released with a lot-specific COA, MSDS and full analytical traceability.

Product Parameters

Item	Specification
Product Name	Spermidine
Synonyms	N-(3-Aminopropyl)-1,4-butanediamine; 1,4-Butanediamine, N-(3-aminopropyl)-
CAS No.	124-20-9 (free base)
Related CAS	Spermidine trihydrochloride: 334-50-9
Molecular Formula	C7H19N3
Molecular Weight	145.25 g/mol
Appearance	Colorless to slightly yellow liquid or low-melting solid
Melting Point	23-25 C
Boiling Point	128-130 C (14 mmHg)
Density	1.00 g/mL at 20 C
Purity	>=98.0% (GC); >=99.0% available on request
Identity	Confirmed by GC-MS and NMR
Grade	Research grade
Moisture	Karl Fischer (lot-specific)
Storage	Inert gas (argon) atmosphere, protected from light and moisture; 2-8 C recommended
Hazard Class	Corrosive (C); UN 2735, Class 8, PG II
HS Code	2921.29.00
Packaging	1 g / 5 g / 10 g / 50 g / 100 g amber glass vial under argon; bulk on request
MOQ	10 g (research grade); 100 g (bulk)
Supply Ability	Gram to kilogram scale
Application	Laboratory research use only
Origin	China

Product Details

1. Overview

Spermidine is a naturally occurring polyamine found in all living organisms and is involved in the regulation of diverse cellular processes including DNA synthesis, cell proliferation and differentiation. It is widely used as a pharmaceutical intermediate and biochemical research reagent. Knowlux supplies spermidine as a research-grade material; it is not intended for human or veterinary administration, and no therapeutic or supplement claims are made.

2. Research Context (Not a Therapeutic Claim)

Published literature describes spermidine as a polyamine studied in in vitro and in vivo research models, with proposed roles in cellular metabolism, autophagy regulation and gene expression. These descriptions are derived from published research and are provided for scientific reference only. Knowlux makes no claims regarding the efficacy, safety, or suitability of this product for any human or veterinary application. Promotion of spermidine for anti-aging, longevity or autophagy induction is not supported by Knowlux and is inconsistent with research-use-only supply.

3. Quality Control

Test Item	Method
Purity	GC
Identity & molecular mass	GC-MS
Structural confirmation	NMR (on request)
Moisture	Karl Fischer
Appearance	Visual
Residual solvents	GC (on request)
Heavy metals	ICP-MS (on request)

Full COA, MSDS, and lot-specific chromatograms are issued with each shipment.

4. Applications

• Reference standard for analytical method development

• In vitro polyamine metabolism and transport studies

• Research on cellular autophagy and stress response models

• LC-MS and biochemical assay calibrators

5. Packaging, Storage & Shipping

Spermidine is air-sensitive and hygroscopic. Primary packing: amber glass vial or ampoule sealed under argon headspace, with a tight-fitting inert closure. Secondary packing: tamper-evident, light-protected carton with desiccant. Cold-chain shipping with temperature logger where required. UN 2735 Class 8 corrosive labeling applies for transport. COA, MSDS, packing list and certificate of origin issued with each shipment.

6. Documentation Support

Per lot: COA, MSDS, certificate of origin, residual solvent statement, heavy metal statement. Specification summaries and audit support available on a project basis.

About Knowlux

Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China. We serve research groups, CDMOs and distributors in more than 40 countries, and support contract synthesis, custom packaging and technical documentation requests.

Compliance Statement

This product is supplied for laboratory research use only. It is not for human or animal administration, not for diagnostic or therapeutic use, not for retail sale, and not for personal use. Research context statements are for scientific reference only and do not constitute medical advice, promotional claims, or dosing guidance.