Eloralintide (LY3841136) | CAS 2883634-40-8 | Amylin Receptor Agonist | Knowlux

Product Description

Eloralintide, CAS 2883634-40-8, is a synthetic long-acting amylin receptor agonist supplied by Knowlux at ≥98% HPLC purity. It is a 37-amino-acid peptide, C-terminally amidated, with a Cys2–Cys7 bridge and a lipidated side chain that prolongs its duration of action. Its molecular formula is C201H319N49O65S2 and its molecular weight is 4526.10 g/mol (free base). Eloralintide is the development code LY3841136, originated by Eli Lilly.

It acts through the amylin receptor pathway with preferential activity at the AMY1 receptor, a signalling route distinct from GLP-1 and GIP. It is currently in late-stage clinical development for obesity and overweight, and is used in laboratory research on appetite regulation, gastric emptying, satiety signalling and metabolic disease models.

Each lot is released against a lot-specific COA with HPLC and MS data. Identity is confirmed by LC-MS, with peptide content, water content and counter-ion controlled to internal specification. Products are packed in nitrogen-flushed, light-protected vials or foil pouches with desiccant and shipped worldwide with MSDS and export documentation.

Key Attributes

• CAS No.: 2883634-40-8

• Synonym / code: Eloralintide, LY3841136

• Formula: C201H319N49O65S2

• Molecular weight: 4526.10 (free base)

• Sequence length: 37 amino acids, C-terminally amidated, lipidated

• Purity: ≥98% (HPLC)

• Appearance: white to off-white lyophilized powder

• Application: laboratory research

• Grade standard: research grade

• Brand: Knowlux

• Origin: Hubei, China

• MOQ: 1 mg (sample size)

• Packaging: glass vial / aluminium foil bag / fibre drum

• Storage: ?20 °C, protected from light and moisture; reconstituted solution 2–8 °C, use within 7 days

FAQ

Q1: Is Eloralintide the same class as semaglutide or tirzepatide?
A: No. Semaglutide is a GLP-1 receptor agonist and tirzepatide is a GIP/GLP-1 dual agonist; Eloralintide acts on the amylin receptor pathway, preferentially AMY1. Its CAS, formula and sequence differ completely, so the three should never be quoted interchangeably in a specification.

Q2: What is the correct CAS and formula to quote in an RFQ?
A: CAS 2883634-40-8, molecular formula C201H319N49O65S2, molecular weight 4526.10 (free base). Please state the pack size and required purity when requesting a quotation, as prices differ by lot and specification.

Q3: Do you provide a COA for each batch?
A: Yes. Every shipment includes a lot-specific COA with the HPLC trace and MS spectrum. Peptide content, water content and counter-ion are reported per lot; third-party testing can be arranged on request.

Q4: How is the product shipped and stored?
A: Lyophilized powder is shipped ambient or cold-chain in nitrogen-flushed, light-protected vials. Store at ?20 °C away from light and moisture. After reconstitution, keep at 2–8 °C and use within 7 days; avoid repeated freeze-thaw cycles.

About Knowlux

Knowlux Biotechnology is a GMP-oriented manufacturer and supplier of peptides, APIs and fine-chemical research compounds, operating from Hubei, China, and serving research groups, CDMOs and distributors in more than 40 countries. We support contract synthesis, custom packaging and technical documentation requests.